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The Impact of Macroscopic Epistasis on Long-Term Evolutionary Dynamics
Genetic interactions can strongly influence the fitness effects of individual mutations, yet the impact of these epistatic interactions on evolutionary dynamics remains poorly understood. Here we investigate the evolutionary role of epistasis over 50,000 generations in a well-studied laboratory evol...
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| Publié dans: | Genetics |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Genetics Society of America
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4286683/ https://ncbi.nlm.nih.gov/pubmed/25395665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.172460 |
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