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Cavity as a Source of Conformational Fluctuation and High-Energy State: High-Pressure NMR Study of a Cavity-Enlarged Mutant of T4Lysozyme

Although the structure, function, conformational dynamics, and controlled thermodynamics of proteins are manifested by their corresponding amino acid sequences, the natural rules for molecular design and their corresponding interplay remain obscure. In this study, we focused on the role of internal...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Maeno, Akihiro, Sindhikara, Daniel, Hirata, Fumio, Otten, Renee, Dahlquist, Frederick W., Yokoyama, Shigeyuki, Akasaka, Kazuyuki, Mulder, Frans A.A., Kitahara, Ryo
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286597/
https://ncbi.nlm.nih.gov/pubmed/25564860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.11.012
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