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Synonymous Mutations Reduce Genome Compactness in Icosahedral ssRNA Viruses

Recent studies have shown that single-stranded (ss) viral RNAs fold into more compact structures than random RNA sequences with similar chemical composition and identical length. Based on this comparison, it has been suggested that wild-type viral RNA may have evolved to be atypically compact so as...

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Vydáno v:Biophys J
Hlavní autoři: Tubiana, Luca, Božič, Anže Lošdorfer, Micheletti, Cristian, Podgornik, Rudolf
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286596/
https://ncbi.nlm.nih.gov/pubmed/25564866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.10.070
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