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Identification of a new pharmacological activity of the phenylpiperazine derivative naftopidil: tubulin-binding drug

The phenylpiperazine derivative naftopidil is an α(1)-adrenoceptor (AR) antagonist that has been used clinically to treat benign prostatic hyperplasia. In our drug repositioning research, naftopidil shows the unique growth-inhibitory effects. Naftopidil inhibits cell cycle progression not only in ca...

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Detalhes bibliográficos
Publicado no:J Chem Biol
Main Authors: Ishii, Kenichiro, Sugimura, Yoshiki
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286570/
https://ncbi.nlm.nih.gov/pubmed/25584077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-014-0122-0
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