Electrostatic Interactions Between the Bni1p Formin FH2 Domain and Actin Influence Actin Filament Nucleation

Formins catalyze nucleation and growth of actin filaments. Here we study the structure and interactions of actin with the FH2 domain of budding yeast formin Bni1p. We built an all-atom model of the formin dimer on an Oda actin filament 7-mer and studied structural relaxation and inter-protein intera...

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Bibliografiske detaljer
Udgivet i:Structure
Main Authors: Baker, Joseph L., Courtemanche, Naomi, Parton, Daniel L., McCullagh, Martin, Pollard, Thomas D., Voth, Gregory A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286494/
https://ncbi.nlm.nih.gov/pubmed/25482541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.10.014
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