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Mitochondrial Dysfunction in Peripheral Blood Mononuclear Cells in Pediatric Septic Shock

OBJECTIVE: Mitochondrial dysfunction in peripheral blood mononuclear cells (PBMCs) has been linked to immune dysregulation and organ failure in adult sepsis but pediatric data are limited. We hypothesized that pediatric septic shock patients exhibit mitochondrial dysfunction within PBMCs which in tu...

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Detalhes bibliográficos
Publicado no:Pediatr Crit Care Med
Main Authors: Weiss, Scott L., Selak, Mary A., Tuluc, Florin, Villarroel, Jose Perales, Nadkarni, Vinay M., Deutschman, Clifford S., Becker, Lance B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286436/
https://ncbi.nlm.nih.gov/pubmed/25251517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PCC.0000000000000277
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