The cyclic AMP pathway is a sex-specific modifier of glioma risk in type 1 neurofibromatosis patients

Identifying modifiers of glioma risk in patients with type 1 neurofibromatosis (NF1) could help support personalized tumor surveillance, advance understanding of gliomagenesis and potentially identify novel therapeutic targets. Here we report genetic polymorphisms in the human adenylate cyclase gene...

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Pubblicato in:Cancer Res
Autori principali: Warrington, Nicole M., Sun, Tao, Luo, Jingqin, McKinstry, Robert C., Parkin, Patricia C., Ganzhorn, Sara, Spoljaric, Debra, Albers, Anne C., Merkelson, Amanda, Stewart, Douglas R., Stevenson, David A., Viskochil, David, Druley, Todd E., Forys, Jason T, Reilly, Karlyne M., Fisher, Michael J., Tabori, Uri, Allen, Jeffrey C., Schiffman, Joshua D., Gutmann, David H., Rubin, Joshua B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286430/
https://ncbi.nlm.nih.gov/pubmed/25381154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1891
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