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The cyclic AMP pathway is a sex-specific modifier of glioma risk in type 1 neurofibromatosis patients

Identifying modifiers of glioma risk in patients with type 1 neurofibromatosis (NF1) could help support personalized tumor surveillance, advance understanding of gliomagenesis and potentially identify novel therapeutic targets. Here we report genetic polymorphisms in the human adenylate cyclase gene...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Warrington, Nicole M., Sun, Tao, Luo, Jingqin, McKinstry, Robert C., Parkin, Patricia C., Ganzhorn, Sara, Spoljaric, Debra, Albers, Anne C., Merkelson, Amanda, Stewart, Douglas R., Stevenson, David A., Viskochil, David, Druley, Todd E., Forys, Jason T, Reilly, Karlyne M., Fisher, Michael J., Tabori, Uri, Allen, Jeffrey C., Schiffman, Joshua D., Gutmann, David H., Rubin, Joshua B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286430/
https://ncbi.nlm.nih.gov/pubmed/25381154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1891
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