A novel systemically administered toll-like receptor 7 agonist potentiates the effect of ionizing radiation in murine solid tumor models

Although topical TLR7 therapies such as imiquimod have proved successful in the treatment of dermatological malignancy, systemic delivery may be required for optimal immunotherapy of nondermatological tumors. We report that intravenous delivery of the novel small molecule TLR7 agonist, DSR-6434, lea...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Int J Cancer
Päätekijät: Adlard, Amy L, Dovedi, Simon J, Telfer, Brian A, Koga-Yamakawa, Erina, Pollard, Charlotte, Honeychurch, Jamie, Illidge, Timothy M, Murata, Masashi, Robinson, David T, Jewsbury, Philip J, Wilkinson, Robert W, Stratford, Ian J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BlackWell Publishing Ltd 2014
Aiheet:
Tumor Immunology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286010/
https://ncbi.nlm.nih.gov/pubmed/24390981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28711
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