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Carbohydrate-Dependent Binding of Langerin to SodC, a Cell Wall Glycoprotein of Mycobacterium leprae

Langerhans cells participate in the immune response in leprosy by their ability to activate T cells that recognize the pathogen, Mycobacterium leprae, in a langerin-dependent manner. We hypothesized that langerin, the distinguishing C-type lectin of Langerhans cells, would recognize the highly manno...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Kim, Hee Jin, Brennan, Patrick J., Heaslip, Darragh, Udey, Mark C., Modlin, Robert L., Belisle, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285976/
https://ncbi.nlm.nih.gov/pubmed/25422308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02080-14
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