Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene

BACKGROUND: Gemcitabine is an analogue of deoxycytidine with activity against several solid tumors. In order to elucidate the mechanisms by which tumor cells become resistant to gemcitabine, we developed the resistant subline RL-G from the human follicular lymphoma cell line RL-7 by prolonged exposu...

Full description

Saved in:
Bibliographic Details
Main Authors: Galmarini, Carlos María, Clarke, Marilyn L, Jordheim, Lars, Santos, Cheryl L, Cros, Emeline, Mackey, John R, Dumontet, Charles
Format: Artigo
Language:Inglês
Published: BioMed Central 2004
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC428575/
https://ncbi.nlm.nih.gov/pubmed/15157282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-4-8
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items