Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene

BACKGROUND: Gemcitabine is an analogue of deoxycytidine with activity against several solid tumors. In order to elucidate the mechanisms by which tumor cells become resistant to gemcitabine, we developed the resistant subline RL-G from the human follicular lymphoma cell line RL-7 by prolonged exposu...

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Detalhes bibliográficos
Main Authors: Galmarini, Carlos María, Clarke, Marilyn L, Jordheim, Lars, Santos, Cheryl L, Cros, Emeline, Mackey, John R, Dumontet, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC428575/
https://ncbi.nlm.nih.gov/pubmed/15157282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-4-8
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