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Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene

BACKGROUND: Gemcitabine is an analogue of deoxycytidine with activity against several solid tumors. In order to elucidate the mechanisms by which tumor cells become resistant to gemcitabine, we developed the resistant subline RL-G from the human follicular lymphoma cell line RL-7 by prolonged exposu...

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書誌詳細
主要な著者: Galmarini, Carlos María, Clarke, Marilyn L, Jordheim, Lars, Santos, Cheryl L, Cros, Emeline, Mackey, John R, Dumontet, Charles
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC428575/
https://ncbi.nlm.nih.gov/pubmed/15157282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-4-8
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