CD39 improves survival in microbial sepsis by attenuating systemic inflammation

Sepsis remains the leading cause of morbidity and mortality in critically ill patients. Excessive inflammation is a major cause of organ failure and mortality in sepsis. Ectonucleoside triphosphate diphosphohydrolase 1, ENTPDase1 (CD39) is a cell surface nucleotide-metabolizing enzyme, which degrade...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Csóka, Balázs, Németh, Zoltán H., Törő, Gábor, Koscsó, Balázs, Kókai, Endre, Robson, Simon C., Enjyoji, Keiichi, Rolandelli, Rolando H., Erdélyi, Katalin, Pacher, Pál, Haskó, György
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285550/
https://ncbi.nlm.nih.gov/pubmed/25318479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-253567
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