STAT3 paradoxically stimulates β-catenin expression but inhibits β-catenin function

Wnt signalling and the signal transducer and activator of transcription 3 (STAT3) are oncogenic signalling pathways which are deregulated in colorectal cancer (CRC). Here we investigated the interaction of these two pathways. Firstly, we investigated biochemical interaction by inhibiting STAT3 and β...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Exp Pathol
Auteurs principaux: Ibrahem, Salih, Al-Ghamdi, Saleh, Baloch, Kanwal, Muhammad, Belal, Fadhil, Wakkas, Jackson, Darryl, Nateri, Abdolrahman S, Ilyas, Mohammad
Format: Artigo
Langue:Inglês
Publié: BlackWell Publishing Ltd 2014
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285465/
https://ncbi.nlm.nih.gov/pubmed/25348333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12102
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