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CD4 T Cells Mediate Both Positive and Negative Regulation of the Immune Response to HIV Infection: Complex Role of T Follicular Helper Cells and Regulatory T Cells in Pathogenesis

HIV-1 infection results in chronic activation of cells in lymphoid tissue, including T cells, B-cells, and myeloid lineage cells. The resulting characteristic hyperplasia is an amalgam of proliferating host immune cells in the adaptive response, increased concentrations of innate response mediators...

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Pubblicato in:Front Immunol
Autori principali: Phetsouphanh, Chansavath, Xu, Yin, Zaunders, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285174/
https://ncbi.nlm.nih.gov/pubmed/25610441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00681
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