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Click chemistry facilitates direct labelling and super-resolution imaging of nucleic acids and proteins
We demonstrate high-density labelling of cellular DNA and RNA using click chemistry and perform confocal and super-resolution microscopy. We visualize the crescent and ring-like structure of densely packed RNA in nucleoli. We further demonstrate click chemistry with unnatural amino acids for super-r...
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| Udgivet i: | RSC Adv |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Royal Society of Chemistry
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4285124/ https://ncbi.nlm.nih.gov/pubmed/25580242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ra01027b |
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