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Retrospective Review of Combined Sirolimus and Simvastatin Therapy in Lymphangioleiomyomatosis
BACKGROUND: Combined simvastatin and sirolimus therapy reduces tuberous sclerosis complex 2-null lesions and alveolar destruction in a mouse model of lymphangioleiomyomatosis (LAM), suggesting that therapy with both drugs may benefit patients with LAM. METHODS: To determine whether simvastatin chang...
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| Publicado no: | Chest |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American College of Chest Physicians
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4285076/ https://ncbi.nlm.nih.gov/pubmed/25167325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1378/chest.14-0758 |
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