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Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature

Despite the inarguable relevance of p53 in cancer, genome-wide studies relating endogenous p53 activity to the expression of lncRNAs in human cells are still missing. Here, by integrating RNA-seq with p53 ChIP-seq analyses of a human cancer cell line under DNA damage, we define a high-confidence set...

詳細記述

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書誌詳細
出版年:Nat Commun
主要な著者: Sánchez, Yolanda, Segura, Victor, Marín-Béjar, Oskar, Athie, Alejandro, Marchese, Francesco P., González, Jovanna, Bujanda, Luis, Guo, Shuling, Matheu, Ander, Huarte, Maite
フォーマット: Artigo
言語:Inglês
出版事項: Nature Pub. Group 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284803/
https://ncbi.nlm.nih.gov/pubmed/25524025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6812
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