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Lidocaine Sensitizes the Cytotoxicity of Cisplatin in Breast Cancer Cells via Up-Regulation of RARβ2 and RASSF1A Demethylation

It has been reported that lidocaine is toxic to various types of cells. And a recent study has confirmed that lidocaine exerts a demethylation effect and regulates the proliferation of human breast cancer cell lines. To recognize a potential anti-tumor effect of lidocaine, we evaluated the DNA demet...

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Publicat a:Int J Mol Sci
Autors principals: Li, Kehan, Yang, Jianxue, Han, Xuechang
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284778/
https://ncbi.nlm.nih.gov/pubmed/25526566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms151223519
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