AMP-activated protein kinase (AMPK) as a potential therapeutic target independent of PI3K/Akt signaling in prostate cancer

Depletion of cellular energy activates the AMP-activated kinase (AMPK) to favor energy-producing catabolic processes during tumorigenesis. Using a panel of in vitro cell lines and resected tumors, we investigated the therapeutic value of manipulating AMPK in prostate cancer (PC). Phospho-AMPK expres...

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Detalhes bibliográficos
Publicado no:Oncoscience
Main Authors: Choudhury, Yashmin, Yang, Zichu, Ahmad, Imran, Nixon, Colin, Salt, Ian P., Leung, Hing Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284621/
https://ncbi.nlm.nih.gov/pubmed/25594043
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