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Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis

Sepsis is characterized by overlapping phases of excessive inflammation temporally aligned with an immunosuppressed state, defining a complex clinical scenario that explains the lack of successful therapeutic options. Here we tested whether the formyl-peptide receptor 2/3 (Fpr2/3)—ortholog to human...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Gobbetti, Thomas, Coldewey, Sina M., Chen, Jianmin, McArthur, Simon, le Faouder, Pauline, Cenac, Nicolas, Flower, Roderick J., Thiemermann, Christoph, Perretti, Mauro
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284560/
https://ncbi.nlm.nih.gov/pubmed/25512512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410938111
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