Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase.
An efficient method of transgene modulation in fertilized eggs has been developed that uses the Cre/loxP recombination system. Twelve transgenic mouse lines carrying a chicken beta-actin promoter-loxP-chloramphenicol acetyltransferase (CAT) gene-loxP-beta-galactosidase gene construct were produced....
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1995
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42837/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7816809/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.1.160 |
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