Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase.

An efficient method of transgene modulation in fertilized eggs has been developed that uses the Cre/loxP recombination system. Twelve transgenic mouse lines carrying a chicken beta-actin promoter-loxP-chloramphenicol acetyltransferase (CAT) gene-loxP-beta-galactosidase gene construct were produced....

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Araki, K, Araki, M, Miyazaki, J, Vassalli, P
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42837/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7816809/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.1.160
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