Platelet hemostasis in patients with metabolic syndrome and type 2 diabetes mellitus: cGMP- and NO-dependent mechanisms in the insulin-mediated platelet aggregation

Patients with metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM) have high risk of microcirculation complications and microangiopathies. An increase in thrombogenic risk is associated with platelet hyperaggregation, hypercoagulation, and hyperfibrinolysis. Factors leading to platelet acti...

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Gepubliceerd in:Front Physiol
Hoofdauteurs: Suslova, Tatiana E., Sitozhevskii, Alexei V., Ogurkova, Oksana N., Kravchenko, Elena S., Kologrivova, Irina V., Anfinogenova, Yana, Karpov, Rostislav S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2015
Onderwerpen:
Physiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283519/
https://ncbi.nlm.nih.gov/pubmed/25601838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00501
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