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Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity

Nuclear pore complexes (NPCs) conduct massive transport mediated by shuttling nuclear transport receptors (NTRs), while keeping nuclear and cytoplasmic contents separated. The NPC barrier in Xenopus relies primarily on the intrinsically disordered FG domain of Nup98. We now observed that Nup98 FG do...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Schmidt, Hermann Broder, Görlich, Dirk
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283134/
https://ncbi.nlm.nih.gov/pubmed/25562883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04251
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