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Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes

Antibodies are critical for defence against a variety of microbes but may also be pathogenic in some autoimmune diseases. Many effector functions of antibody are mediated by Fcγ receptors (FcγRs), which are found on most immune cells, including dendritic cells (DCs). DCs are important antigen presen...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Clatworthy, Menna R., Aronin, Caren E. Petrie, Mathews, Rebeccah J., Morgan, Nicole, Smith, Kenneth G.C., Germain, Ronald N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283039/
https://ncbi.nlm.nih.gov/pubmed/25384086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3709
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