Genetic Predisposition to Papillary Thyroid Carcinoma: Involvement of FOXE1, TSHR, and a Novel lincRNA Gene, PTCSC2

CONTEXT: By genome-wide association studies, the risk allele [A] of SNP rs965513 predisposes strongly to papillary thyroid carcinoma (PTC). It is located in a gene-poor region of 9q22, some 60 kb from the FOXE1 gene. The underlying mechanisms remain to be discovered. OBJECTIVE: Our objective was to...

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Pubblicato in:J Clin Endocrinol Metab
Autori principali: He, Huiling, Li, Wei, Liyanarachchi, Sandya, Jendrzejewski, Jaroslaw, Srinivas, Mukund, Davuluri, Ramana V., Nagy, Rebecca, de la Chapelle, Albert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2015
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JCEM Online: Advances in Genetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283026/
https://ncbi.nlm.nih.gov/pubmed/25303483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-2147
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