Thyroid Hormone Receptor β (THRB) Is a Major Target Gene for MicroRNAs Deregulated in Papillary Thyroid Carcinoma (PTC)

CONTEXT: Loss of the thyroid hormone receptor is common in tumors. In mouse models, a truncated THRB gene leads to thyroid cancer. Previously, we observed up-regulation of the expression of eight microRNAs (miRs) in papillary thyroid carcinoma (PTC) tumors. OBJECTIVE: Our objective was to determine...

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Detalhes bibliográficos
Main Authors: Jazdzewski, Krystian, Boguslawska, Joanna, Jendrzejewski, Jaroslaw, Liyanarachchi, Sandya, Pachucki, Janusz, Wardyn, Kazimierz A., Nauman, Alicja, de la Chapelle, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
JCEM Online: Advances in Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047217/
https://ncbi.nlm.nih.gov/pubmed/21159845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-1594
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