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Adult Aortic Valve Interstitial Cells Have Greater Responses to Toll-Like Receptor 4 Stimulation
BACKGROUND: Aortic valve interstitial cells (AVICs) have been implicated in the pathogenesis of calcific aortic valve disease. Signal transducer and activator of transcription 3 (Stat3) possesses antiinflammatory effects. Given that calcification occurs in adult valves, we hypothesized that AVICs fr...
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| 出版年: | Ann Thorac Surg |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282986/ https://ncbi.nlm.nih.gov/pubmed/25442996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2014.07.027 |
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