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A single amino acid change in inhibitory killer cell Ig-like receptor results in constitutive receptor self-association and phosphorylation
Signaling by immunoreceptors is often initiated by phosphorylation of cytosolic tyrosines, which then recruit effector molecules. In the case of MHC class I-specific inhibitory receptors, phosphorylation of cytosolic tyrosine residues within immunoreceptor tyrosine-based inhibition motifs (ITIM) res...
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| Pubblicato in: | J Immunol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282981/ https://ncbi.nlm.nih.gov/pubmed/25505289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401830 |
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