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Using drug response data to identify molecular effectors, and molecular “omic” data to identify candidate drugs in cancer

The current convergence of molecular and pharmacological data provides unprecedented opportunities to gain insights into the relationships between the two types of data. Multiple forms of large scale molecular data, including but not limited to gene and microRNA transcript expression, DNA somatic an...

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Vydáno v:Hum Genet
Hlavní autoři: Reinhold, William C., Varma, Sudhir, Rajapakse, Vinodh N., Luna, Augustin, Sousa, Fabricio Garmus, Kohn, Kurt W., Pommier, Yves G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282979/
https://ncbi.nlm.nih.gov/pubmed/25213708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-014-1482-9
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