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Chromosome Band 7q34 Deletions Resulting in KIAA 1549‐ BRAF and FAM 131 B ‐ BRAF Fusions in Pediatric Low‐Grade Gliomas
The majority of pediatric low‐grade gliomas (LGGs) are characterized by constitutive activation of the mitogen‐activated protein kinase (MAPK) pathway through various mechanisms including BRAF mutations, inactivation of NF 1, and KIAA 1549‐ BRAF and FAM 131 B ‐ BRAF fusions. The KIAA 1549‐ BRAF fusi...
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| Publicado no: | Brain Pathol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282976/ https://ncbi.nlm.nih.gov/pubmed/25040262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12167 |
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