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Transmembrane channel-like (TMC) genes are required for auditory and vestibular mechanosensation

Mutations of the transmembrane channel-like 1 (TMC1) gene can cause dominant and recessive forms of deafness in humans and mice. TMC1 is one of eight mammalian TMC genes of unknown function. The multi-pass transmembrane topologic structure of the proteins they encode suggests roles as a receptor, tr...

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Detalhes bibliográficos
Publicado no:Pflugers Arch
Main Authors: Kawashima, Yoshiyuki, Kurima, Kiyoto, Pan, Bifeng, Griffith, Andrew J., Holt, Jeffrey R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282624/
https://ncbi.nlm.nih.gov/pubmed/25074487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-014-1582-3
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