Delayed methotrexate excretion in infants and young children with primary central nervous system tumors and postoperative fluid collections

PURPOSE: High-dose methotrexate (HD-MTX) has been used to treat children with central nervous system tumors. Accumulation of MTX within pleural, peritoneal, or cardiac effusions has led to delayed excretion and increased risk of systemic toxicity. This retrospective study analyzed the association of...

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Gepubliceerd in:Cancer Chemother Pharmacol
Hoofdauteurs: Wright, Karen D., Panetta, John C., Onar-Thomas, Arzu, Reddick, Wilburn E., Patay, Zoltan, Qaddoumi, Ibrahim, Broniscer, Alberto, Robinson, Giles, Boop, Frederick A., Klimo, Paul, Ward, Deborah, Gajjar, Amar, Stewart, Clinton F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282603/
https://ncbi.nlm.nih.gov/pubmed/25342291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2614-6
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