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Chapter 13: Carbonic Anhydrase IX as an Imaging and Therapeutic Target for Tumors and Metastases

Carbonic anhydrase IX (CAIX) which is a zinc containing metalloprotein, efficiently catalyzes the reversible hydration of carbon dioxide. It is constitutively up-regulated in several cancer types and has an important role in tumor progression, acidification and metastasis. High expression of CAIX ge...

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Detalhes bibliográficos
Publicado no:Subcell Biochem
Main Authors: Tafreshi, Narges K., Lloyd, Mark C., Bui, Marilyn M., Gillies, Robert J., Morse, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282494/
https://ncbi.nlm.nih.gov/pubmed/24146382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-94-007-7359-2_12
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