Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure

The pathogenesis and therapy of Shigatoxin 2 (Stx2)-mediated kidney failure remain controversial. Our aim was to test whether, during an infection with Stx2-producing E. coli (STEC), Stx2 exerts direct effects on renal tubular epithelium and thereby possibly contributes to acute renal failure. Mice...

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Vydáno v:J Pathol
Hlavní autoři: Porubsky, Stefan, Federico, Giuseppina, Müthing, Johannes, Jennemann, Richard, Gretz, Norbert, Büttner, Stefan, Obermüller, Nicholas, Jung, Oliver, Hauser, Ingeborg A, Gröne, Elisabeth, Geiger, Helmut, Gröne, Hermann-Josef, Betz, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2014
Témata:
Original Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282478/
https://ncbi.nlm.nih.gov/pubmed/24909663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4388
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