Influence of Native and Hypochlorite-Modified Low-Density Lipoprotein on Gene Expression in Human Proximal Tubular Epithelium

Inflammatory infiltrates can modify (lipo)proteins via hypochlorous acid/hypochlorite (HOCl/OCl(−)) an oxidant formed by the myeloperoxidase-H(2)O(2)-halide system. These oxidatively modified proteins emerge in tubuli in some proteinuric and interstitial diseases. Human proximal tubular cells (HK-2)...

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Main Authors: Porubsky, Stefan, Schmid, Holger, Bonrouhi, Mahnaz, Kretzler, Matthias, Malle, Ernst, Nelson, Peter J., Gröne, Hermann-Josef
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
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Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615757/
https://ncbi.nlm.nih.gov/pubmed/15161651
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