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Targeting rtPA in acute ischemic stroke based on risk of intracranial hemorrhage or poor functional outcome: an analysis of the IST-3 trial

BACKGROUND AND PURPOSE: Intravenous rtPA, despite a risk of early symptomatic intracranial hemorrhage (SICH), is of net clinical benefit to acute stroke patients. We tested if predictive models could identify patients least likely to be harmed by SICH or those who gained no net benefit. METHODS: We...

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Bibliographische Detailangaben
Veröffentlicht in:Stroke
Hauptverfasser: Whiteley, William N., Thompson, Douglas, Murray, Gordon, Cohen, Geoff, Lindley, Richard I., Wardlaw, Joanna, Sandercock, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282175/
https://ncbi.nlm.nih.gov/pubmed/24603072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.113.004362
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