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The Superiority of the Time-to-Event Continual Reassessment Method to the Rolling Six Design in Pediatric Oncology Phase I Trials
BACKGROUND: The Rolling Six Design (RSD) is currently being used by the Children’s Oncology Group (COG) as their standard design for Phase I trials. Because the COG has large multi-center trials with fast accrual, the motivation for adopting the RSD is to hasten accrual and shorten the duration of t...
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| Pubblicato in: | Clin Trials |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281887/ https://ncbi.nlm.nih.gov/pubmed/21610004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774511407533 |
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