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Increased Levels of β-catenin, LEF-1, and HPA-1 Correlate with Poor Prognosis for Acral Melanoma with Negative BRAF and NRAS Mutation in BRAF Exons 11 and 15 and NRAS Exons 1 and 2

To determine the expression of β-catenin, lymphoid enhancer-binding protein-1 (LEF-1), and heparanase-1 (HPA-1) and to evaluate these proteins' potential prognostic values in malignant acral melanoma without mutations in BRAF exons 11 and 15 and NRAS exons 1 and 2, specimens from 90 patients wi...

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Detalhes bibliográficos
Publicado no:DNA Cell Biol
Main Authors: Xu, Sanxiong, Yang, Zuozhang, Zhang, Jinyu, Jiang, Yongxin, Chen, Yongbin, Li, Hongjun, Liu, Xuefeng, Xu, Da, Chen, Yanjin, Yang, Yihao, Zhang, Ya, Li, Dongxu, Xia, Junfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281839/
https://ncbi.nlm.nih.gov/pubmed/25343173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2014.2590
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