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CDK6 is a regulator of stem cells “Egr” to wake up
In this issue of Blood, Scheicher et al show that cyclin-dependent kinase 6 (CDK6) has a novel role in the regulation of both normal and leukemic stem cells. It acts as a transcriptional suppressor of Egr1, enabling it to control both normal and leukemic stem cell activation.(1)
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| Publicado no: | Blood |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281831/ https://ncbi.nlm.nih.gov/pubmed/25554744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-11-609230 |
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