Загрузка...
The First Crystal Structure of a dTTP-bound Deoxycytidylate Deaminase Validates and Details the Allosteric-Inhibitor Binding Site
Deoxycytidylate deaminase is unique within the zinc-dependent cytidine deaminase family as being allosterically regulated, activated by dCTP, and inhibited by dTTP. Here we present the first crystal structure of a dTTP-bound deoxycytidylate deaminase from the bacteriophage S-TIM5, confirming that th...
Сохранить в:
| Опубликовано в: : | J Biol Chem |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2015
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281768/ https://ncbi.nlm.nih.gov/pubmed/25404739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.617720 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|