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p38 MAPK activation upregulates proinflammatory pathways in skeletal muscle cells from insulin-resistant type 2 diabetic patients
Skeletal muscle is the key site of peripheral insulin resistance in type 2 diabetes. Insulin-stimulated glucose uptake is decreased in differentiated diabetic cultured myotubes, which is in keeping with a retained genetic/epigenetic defect of insulin action. We investigated differences in gene expre...
Gardado en:
| Publicado en: | Am J Physiol Endocrinol Metab |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281683/ https://ncbi.nlm.nih.gov/pubmed/25370850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00115.2014 |
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