CD44 variant isoforms expressed by breast cancer cells are functional E-selectin ligands under flow conditions

Adhesion of circulating tumor cells to vascular endothelium is mediated by specialized molecules that are functional under shear forces exerted by hematogenous flow. Endothelial E-selectin binding to glycoforms of CD44 mediates shear-resistant cell adhesion in numerous physiological and pathological...

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Vydáno v:Am J Physiol Cell Physiol
Hlavní autoři: Shirure, Venktesh S., Liu, Tiantian, Delgadillo, Luis F., Cuckler, Chaz M., Tees, David F. J., Benencia, Fabian, Goetz, Douglas J., Burdick, Monica M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281670/
https://ncbi.nlm.nih.gov/pubmed/25339657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00094.2014
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