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Stably paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor triptolide

Transcription by RNA polymerase II (Pol II) in metazoans is regulated in several steps, including preinitiation complex (PIC) formation, initiation, Pol II escape, productive elongation, cotranscriptional RNA processing, and termination. Genome-wide studies have demonstrated that the phenomenon of p...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Chen, Fei, Gao, Xin, Shilatifard, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281563/
https://ncbi.nlm.nih.gov/pubmed/25561494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.246173.114
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