Involvement of DNA polymerase beta overexpression in the malignant transformation induced by benzo[a]pyrene

OBJECTIVE: To explore the relationship between DNA polymerase β (pol β) overexpression and benzo[a]pyrene (BaP) carcinogenesis. METHODS: Firstly, mouse embryonic fibroblasts that express wild-type level of DNA polymerase β (pol β cell) and high level of pol β (pol β oe cell) were treated by various...

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Published in:Toxicology
Main Authors: Zhao, Wei, Wu, Mei, Lai, Yanhao, Deng, Wenwen, Liu, Yuan, Zhang, Zunzhen
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281483/
https://ncbi.nlm.nih.gov/pubmed/23652152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2013.04.017
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