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Alterations in the Smad pathway in human cancers

Members of the TGF-beta superfamily exhibit various biological activities, and perturbations of their signaling are linked to certain clinical disorders including cancer. The role of TGF-beta signaling as a tumor suppressor pathway is best illustrated by the presence of inactivating mutations in gen...

詳細記述

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書誌詳細
出版年:Front Biosci (Landmark Ed)
主要な著者: Samanta, Debangshu, Datta, Pran K.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281477/
https://ncbi.nlm.nih.gov/pubmed/22201803
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