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Developmental regulation of human cortex transcription and its clinical relevance at base resolution

Transcriptome analysis of human brain provides fundamental insight about development and disease, but largely relies on existing annotation. We sequenced transcriptomes of 72 prefrontal cortex samples across six life stages, and identified 50,650 differentially expression regions (DERs) associated w...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Jaffe, Andrew E., Shin, Jooheon, Collado-Torres, Leonardo, Leek, Jeffrey T., Tao, Ran, Li, Chao, Gao, Yuan, Jia, Yankai, Maher, Brady J., Hyde, Thomas M., Kleinman, Joel E., Weinberger, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281298/
https://ncbi.nlm.nih.gov/pubmed/25501035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3898
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