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Side effect profile of 5-HT treatments for Parkinson's disease and L-DOPA-induced dyskinesia in rats

BACKGROUND AND PURPOSE: Treatment of Parkinson's disease (PD) with L-DOPA eventually causes abnormal involuntary movements known as dyskinesias in most patients. Dyskinesia can be reduced using compounds that act as direct or indirect agonists of the 5-HT(1)(A) receptor, but these drugs have be...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Lindenbach, D, Palumbo, N, Ostock, C Y, Vilceus, N, Conti, M M, Bishop, C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280972/
https://ncbi.nlm.nih.gov/pubmed/25175895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12894
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