Oxidized LDL-induced angiogenesis involves sphingosine 1-phosphate: prevention by anti-S1P antibody

BACKGROUND AND PURPOSE: Neovascularization occurring in atherosclerotic lesions may promote plaque expansion, intraplaque haemorrhage and rupture. Oxidized LDL (oxLDL) are atherogenic, but their angiogenic effect is controversial; both angiogenic and anti-angiogenic effects have been reported. The a...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Camaré, Caroline, Trayssac, Magali, Garmy-Susini, Barbara, Mucher, Elodie, Sabbadini, Roger, Salvayre, Robert, Negre-Salvayre, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2015
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280971/
https://ncbi.nlm.nih.gov/pubmed/25176316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12897
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